{
  "id": 7382938,
  "title": "Ageing reshapes the resting-state network landscape of the human brain",
  "url": "https://urgent.news/2026/09/14/ageing-reshapes-the-resting-state-network-landscape-of-the-human-brain",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-14T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.07.749858v1?rss=1"
  },
  "original_language": "en",
  "account": "A study has revealed that aging brings about significant changes in the brain's resting-state network, affecting its frequency organization and spatial expression. Using Frequency-resolved Network Estimation via Source Separation (FREQ-NESS) on resting-state MEG data from 164 healthy younger and older adults, researchers found that older adults exhibit altered alpha-network peak frequencies and a flatter decay of network prominence from alpha to beta frequencies. These spectral variations were accompanied by shifts in the spatial distribution of dominant networks along the lateral, posterior-anterior, and inferior-superior axes. Unlike a uniform anatomical shift, the impact of aging varied depending on the frequency, suggesting a selective reconfiguration of whole-brain activity prominence and spatiotemporal expression. Overall, the findings indicate that healthy aging is characterized by a reshaped configuration of endogenous brain networks, rather than a simple loss of network organization.",
  "summary": "Ageing alters brain rhythms and large-scale functional organisation, but whether these changes reflect isolated effects or a coordinated reconfiguration remains unclear. We applied Frequency-resolved Network Estimation via Source Separation (FREQ-NESS) to source-reconstructed resting-state MEG from 164 healthy younger and older adults across two independent datasets. FREQ-NESS revealed that…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}