{
  "id": 7330442,
  "title": "De novo mutations bridge parental reproductive factors and offspring health",
  "url": "https://urgent.news/2026/09/14/de-novo-mutations-bridge-parental-reproductive-factors-and-offspring",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-09-14T00:00:00.000Z",
  "source": {
    "name": "Nature Medicine",
    "slug": "nature-medicine",
    "url": "https://www.nature.com/articles/s41591-026-04676-0"
  },
  "original_language": "en",
  "account": null,
  "summary": "Nature Medicine, Published online: 14 September 2026; doi:10.1038/s41591-026-04676-0 Whole-genome sequencing of 7,851 parent–offspring families enabled the identification of parent-of-origin and post-zygotic de novo mutations that were associated with distinct procedures of assisted reproductive technology (ART), independently of parental age at conception. Increased paternal mutational burden…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}