{
  "id": 6713167,
  "title": "GOlien tool: fast and scalable GO term annotation of proteins using a Shannon-entropy k-mer model",
  "url": "https://urgent.news/2026/09/10/golien-tool-fast-and-scalable-go-term-annotation-of-proteins-using-a",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-10T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.04.749510v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Automated protein function annotation remains challenging as sequence databases outpace curated labels and homology-based transfer fails for proteins lacking close relatives. We present GOlien, a scalable, composition-based method that annotates protein sequences using a Shannon-entropy k-mer model. Built from the CAFA3-based training split and evaluated on the held-out validation split,…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}