{
  "id": 6533284,
  "title": "CypA is a molecular barrier to HIV emergence from Eastern chimpanzees",
  "url": "https://urgent.news/2026/09/09/cypa-is-a-molecular-barrier-to-hiv-emergence-from-eastern-chimpanzees",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-09-09T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.08.747897v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Of the two lineages of lentivirus that endemically infect chimpanzees, only one has served as a source of infections in hu-mans. Using HIV-CRISPR screening, we identify factors that limit the replication of lentivirus from Eastern chimpanzees. We find that CypA restricts nonzoonotic Eastern chimpanzee lentivirus due to a unique feature encoded in capsid. The ability of CypA to restrict lentivirus…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}