{
  "id": 6351099,
  "title": "AnnoAudit: a marker-based protocol for auditing single-cell atlas annotations reveals annotation-driven artifacts in a widely used traumatic brain injury resource",
  "url": "https://urgent.news/2026/09/08/annoaudit-a-marker-based-protocol-for-auditing-single-cell-atlas",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-08T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.03.749125v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Single-cell atlas annotations are routinely treated as ground truth but rarely validated before use. We present AnnoAudit, a marker-based audit protocol that combines four convergent checks - marker scoring, unsupervised clustering, margin-gated module scoring, and applicability-gated pretrained models - into a composite Annotation Contamination Score (ACS), plus a trajectory-correlation…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}