{
  "id": 6329351,
  "title": "A crystalline sponge reveals structures of large 'beyond rule of 5' molecules",
  "url": "https://urgent.news/2026/09/08/a-crystalline-sponge-reveals-structures-of-large-beyond-rule-of-5",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-08T21:00:07.000Z",
  "source": {
    "name": "Phys.org",
    "slug": "phys-org",
    "url": "https://phys.org/news/2026-09-crystalline-sponge-reveals-large-molecules.html"
  },
  "original_language": "en",
  "account": null,
  "summary": "Drug discovery has traditionally followed the \"rule of 5,\" which identifies chemical properties generally associated with good absorption of orally administered drugs, including a molecular weight below 500 daltons (Da). However, some pharmaceutical compounds fall outside these guidelines. Known as beyond rule of 5 (bRo5) molecules, these compounds can have larger, more complex structures while…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}