{
  "id": 6278090,
  "title": "Super-resolution imaging reveals details inside living cells",
  "url": "https://urgent.news/2026/09/08/super-resolution-imaging-reveals-details-inside-living-cells",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-08T12:40:08.000Z",
  "source": {
    "name": "Phys.org",
    "slug": "phys-org",
    "url": "https://phys.org/news/2026-09-super-resolution-imaging-reveals-cells.html"
  },
  "original_language": "en",
  "account": "A new microscopy technique, SPIFFI, developed by researchers at EPFL's School of Engineering, enables super-resolution imaging of dynamic structures and processes within living cells using just a single camera exposure. SPIFFI, which stands for Spatial Polarization-Induced Fluorescence Fluctuation Imaging, leverages the polarization of fluorescent light to generate detailed images that were previously unattainable with conventional methods.\n\nBy splitting the emitted fluorescent light into four polarization-sensitive channels, SPIFFI effectively visualizes structures around 160-170 nanometers in size, providing a resolution enhancement of up to two times. This allows researchers to observe real-time movements of cellular components such as mitochondria, microtubules, and cellular fusion events, which are challenging to image using traditional methods.\n\nThe technique's ability to capture nanoscale details from a single exposure makes it a valuable tool for a wide range of biological research, including live-cell biology, neuroscience, biophysics, and drug discovery. The SPIFFI setup can be integrated with existing fluorescence microscopes, making it a practical and versatile solution for advancing our understanding of dynamic cellular processes.",
  "summary": "A new fluorescence microscopy technique that generates super-resolution images from a single camera exposure could help researchers study rapid movements within cells that are difficult to capture with existing methods.",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 2,
    "also_reported_by": [
      {
        "outlet": "Phys.org",
        "title": "Super-resolution imaging reveals that cohesin prevents local mixing of compact, active genome domains",
        "url": "https://urgent.news/2026/09/08/super-resolution-imaging-reveals-that-cohesin-prevents-local-mixing",
        "published": "2026-09-08T09:00:09.000Z"
      }
    ]
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}