{
  "id": 6271598,
  "title": "The key to successful treatment of primary aldosteronism: Get it early",
  "url": "https://urgent.news/2026/09/08/the-key-to-successful-treatment-of-primary-aldosteronism-get-it-early",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-09-08T11:20:04.000Z",
  "source": {
    "name": "Medical Xpress",
    "slug": "medical-xpress",
    "url": "https://medicalxpress.com/news/2026-09-key-successful-treatment-primary-aldosteronism.html"
  },
  "original_language": "en",
  "account": "A major international study has found that early treatment of primary aldosteronism (PA) offers the best chance of overcoming this often undetected cause of high blood pressure. Conducted with the help of 48 researchers and nearly 1,300 patients across 27 centers on four continents, the study revealed that targeted medical therapy can bring lasting health benefits. Published in the journal Hypertension, the work, titled Primary Aldosteronism Medical Treatment Outcomes (PAMO) beyond 12 months, highlights the importance of early detection and proper dosing when it comes to successfully managing PA. After a median follow-up of around three years, 82.4% of patients experienced either complete or partial biochemical improvement, while 84.5% achieved either complete or partial clinical improvement. Lead author Professor Jun Yang and co-investigator Dr. Renata Libianto noted that patients diagnosed early, before hypertension and organ damage become established, tend to respond better to treatment. Better clinical outcomes were linked to a shorter history of hypertension and the absence of organ damage at the start of treatment. Adequate spironolactone dosing was associated with improved biochemical response, which in turn is tied to better heart health over the long term. The research underscores the critical role of early diagnosis and personalized treatment in safeguarding the heart and kidney health of those affected by primary aldosteronism.",
  "summary": "Evidence continues to mount regarding the effectiveness of treating primary aldosteronism (PA), with a major international study confirming that early intervention is the best way to beat this hidden cause of hypertension.",
  "key_points": [
    "Early treatment of primary aldosteronism offers best chance of overcoming high blood pressure",
    "Patients diagnosed early before hypertension and organ damage respond better to treatment",
    "Adequate spironolactone dosing associated with improved biochemical response and heart health"
  ],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}