{
  "id": 6225486,
  "title": "RFOptimization: Guiding Design Optimization with All-Atom Structure Prediction",
  "url": "https://urgent.news/2026/09/07/rfoptimization-guiding-design-optimization-with-all-atom-structure",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-07T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.04.749184v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Biomolecular interactions, including protein--protein interactions, protein--nucleic acid recognition, and protein--small molecule binding, underlie a wide range of biological processes and therapeutic mechanisms. Although recent emph{de novo} design methods can generate candidate binders for diverse molecular targets, practical design campaigns remain limited by low filter-passing rates and…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}