{
  "id": 6145415,
  "title": "How losing the 'guardian of the genome' can damage DNA and drive cancer",
  "url": "https://urgent.news/2026/09/07/how-losing-the-guardian-of-the-genome-can-damage-dna-and-drive-cancer",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-07T15:20:01.000Z",
  "source": {
    "name": "Medical Xpress",
    "slug": "medical-xpress",
    "url": "https://medicalxpress.com/news/2026-09-guardian-genome-dna-cancer.html"
  },
  "original_language": "en",
  "account": null,
  "summary": "A new study finds that when p53, one of the most important cancer-protecting genes, stops working, cells produce too much RNA and consume excessive amounts of the building blocks needed to copy their DNA. This shortage disrupts DNA replication, leading to DNA damage, chromosomal instability and major genetic changes that can promote cancer development.",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}