{
  "id": 539475,
  "title": "In vivo mapping of striatal neurodegeneration in Huntington’s disease with Soma and Neurite Density Imaging",
  "url": "https://urgent.news/2026/08/11/in-vivo-mapping-of-striatal-neurodegeneration-in-huntingtons-disease",
  "topic": "ai",
  "section": "AI",
  "published": "2026-08-11T00:00:00.000Z",
  "source": {
    "name": "eLife",
    "slug": "elife",
    "url": "https://elifesciences.org/articles/107661"
  },
  "original_language": "en",
  "account": null,
  "summary": "Huntington’s disease (HD) is an inherited neurodegenerative disorder characterised by progressive cognitive and motor decline driven by basal ganglia (BG) atrophy. Clinical trials of novel disease-modifying therapies are ongoing, creating a need for sensitive non-invasive imaging biomarkers. Soma and Neurite Density Imaging (SANDI) is a multi-shell diffusion MRI model that estimates intracellular…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}