{
  "id": 516180,
  "title": "Presynaptic mechanism of epileptiform activities in forward-programmed human excitatory neuronal networks",
  "url": "https://urgent.news/2026/08/10/presynaptic-mechanism-of-epileptiform-activities-in-forward",
  "topic": "world",
  "section": "World",
  "published": "2026-08-10T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.08.04.742761v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Epilepsy is one of the most common neurological disorders, yet the mechanisms controlling seizure termination remain poorly understood. In particular, why rhythmic spike-wave discharges decelerate before stopping is unexplained. Here, using human iPSC-derived excitatory neurons differentiated via targeted forward-programming, we report a similar deceleration phenomenon in cultured neuronal…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}