{
  "id": 5123590,
  "title": "Autoimmune CAR-T faces tough questions after Novartis, Bristol Myers study halts",
  "url": "https://urgent.news/2026/09/02/autoimmune-car-t-faces-tough-questions-after-novartis-bristol-myers",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-09-02T16:32:00.000Z",
  "source": {
    "name": "BioPharma Dive",
    "slug": "biopharma-dive",
    "url": "https://www.biopharmadive.com/news/autoimmune-cell-therapy-safety-novartis-bristol-kyverna-cabaletta/829413/"
  },
  "original_language": "en",
  "account": null,
  "summary": "Novartis and Bristol Myers Squibb have halted multiple trials of their cell therapy programs for autoimmune conditions due to inflammatory side effects observed during testing. According to BioPharma Dive, Wall Street analysts believe that a more cautious approach to manufacturing, study enrollment, and side effect management could help developers avoid future safety hazards.\n\nThe trials in question involve CAR-T cell therapies, which are being evaluated for their potential to treat autoimmune conditions. The decision to pause the trials was made after inflammatory side effects were observed in patients undergoing treatment.\n\nThe development has raised questions about the future of autoimmune CAR-T therapies. Analysts are suggesting that developers take a more cautious approach to mitigate potential safety risks.",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 2,
    "also_reported_by": [
      {
        "outlet": "Endpoints News",
        "title": "Novartis CAR-T deaths raise questions over acceptable autoimmune risk",
        "url": "https://urgent.news/2026/09/02/novartis-car-t-deaths-raise-questions-over-acceptable-autoimmune-risk",
        "published": "2026-09-02T18:48:44.000Z"
      }
    ]
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}