{
  "id": 4969416,
  "title": "Creating new 3D models to test drugs in pediatric sarcoma: A postdoc's recipe for research",
  "url": "https://urgent.news/2026/09/01/creating-new-3d-models-to-test-drugs-in-pediatric-sarcoma-a-postdocs",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-01T23:40:03.000Z",
  "source": {
    "name": "Medical Xpress",
    "slug": "medical-xpress",
    "url": "https://medicalxpress.com/news/2026-09-3d-drugs-pediatric-sarcoma-postdoc.html"
  },
  "original_language": "en",
  "account": "Allison Reno, a postdoctoral fellow in pediatric sarcoma research, utilizes 3D hydrogel models to test cancer drugs on bone sarcoma, a rare and challenging condition affecting young people. These models are created using a precise combination of rapid temperature changes, acid-based reactions, and gentle mixing to produce a strong gel that mimics human body conditions. The hydrogels incorporate the base components of human tissue, allowing researchers to observe drug diffusion and interaction with the extracellular matrix, which is crucial for understanding drug efficacy and potential side effects in children. Reno's work has led to the creation of patents for these 3D models, making it easier for other research labs to replicate the process. The models have proven to be effective in replicating cell signaling patterns and metastasis, offering a valuable tool for testing both existing and novel drugs before they reach human trials.",
  "summary": "The Great British Bake Off offers drama, baking tips and—for one viewer in South Carolina—inspiration for creating 3D models that can be used to test cancer drugs.",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}