{
  "id": 4706177,
  "title": "Loss of Sall3 eliminates presynaptic inhibition of sensory motor circuits and impairs adaptive motor behavior",
  "url": "https://urgent.news/2026/08/31/loss-of-sall3-eliminates-presynaptic-inhibition-of-sensory-motor",
  "topic": "science",
  "section": "Science",
  "published": "2026-08-31T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.08.25.746905v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Spinal presynaptic inhibitory interneurons are thought to regulate proprioceptive sensory feedback to shape motor output, however, their specific contribution to motor behavior has been difficult to assess, partially due to the lack of a specific genetic handle. Here, we identify Sall3 as the transcription factor required for the establishment and maintenance of GABApre axo-axonic synapses on…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}