{
  "id": 3931675,
  "title": "#ESC26: Trial failure clouds future of AstraZeneca’s heart disease gene silencer",
  "url": "https://urgent.news/2026/08/28/esc26-trial-failure-clouds-future-of-astrazenecas-heart-disease-gene",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-08-28T09:10:19.000Z",
  "source": {
    "name": "Endpoints News",
    "slug": "endpoints-news",
    "url": "https://endpoints.news/esc26-trial-failure-clouds-future-of-astrazenecas-heart-disease-gene-silencer/"
  },
  "original_language": "en",
  "account": null,
  "summary": "MUNICH — The surprise failure of a high-profile study of AstraZeneca’s and Ionis Pharmaceuticals’ Wainua can be attributed to patients in the trial also taking a Pfizer drug for the same condition, the head of the ...",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 3,
    "also_reported_by": [
      {
        "outlet": "SCMP Business",
        "title": "China’s Akeso says cancer drug beat AstraZeneca’s Imfinzi in phase 3 trial",
        "url": "https://urgent.news/2026/08/27/chinas-akeso-says-cancer-drug-beat-astrazenecas-imfinzi-in-phase-3",
        "published": "2026-08-27T02:07:51.000Z"
      },
      {
        "outlet": "BioPharma Dive",
        "title": "New data could widen use of AstraZeneca, Amgen immune disease drug",
        "url": "https://urgent.news/2026/08/27/new-data-could-widen-use-of-astrazeneca-amgen-immune-disease-drug",
        "published": "2026-08-27T15:58:00.000Z"
      }
    ]
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}