{
  "id": 3567266,
  "title": "A rogue neuronal signal may lie at the root of Alzheimer's disease",
  "url": "https://urgent.news/2026/08/26/a-rogue-neuronal-signal-may-lie-at-the-root-of-alzheimers-disease",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-08-26T18:20:05.000Z",
  "source": {
    "name": "Medical Xpress",
    "slug": "medical-xpress",
    "url": "https://medicalxpress.com/news/2026-08-rogue-neuronal-root-alzheimer-disease.html"
  },
  "original_language": "en",
  "account": null,
  "summary": "What if amyloid plaques are not the whole story of Alzheimer's disease? New research suggests that a broad range of Alzheimer's pathologies may be orchestrated by a molecular switch called ERBB4 when it turns on in the wrong neurons. Once activated, this misplaced signal can set off a chain reaction that disrupts brain circuits, eliminates synapses, activates glial cells, increases amyloid…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 4,
    "also_reported_by": [
      {
        "outlet": "bioRxiv",
        "title": "Chronic trazodone treatment consolidates sleep, improves memory, and reduces amyloid pathology in a mouse model of Alzheimer's disease",
        "url": "https://urgent.news/2026/08/25/chronic-trazodone-treatment-consolidates-sleep-improves-memory-and",
        "published": "2026-08-25T00:00:00.000Z"
      },
      {
        "outlet": "Medical Xpress",
        "title": "Deep sleep brain waves offer protection against Alzheimer's disease, new research shows",
        "url": "https://urgent.news/2026/08/25/deep-sleep-brain-waves-offer-protection-against-alzheimers-disease",
        "published": "2026-08-25T19:00:06.000Z"
      },
      {
        "outlet": "Phys.org",
        "title": "Nanoparticles induce neuroregeneration in Alzheimer's disease models",
        "url": "https://urgent.news/2026/08/26/nanoparticles-induce-neuroregeneration-in-alzheimers-disease-models",
        "published": "2026-08-26T15:00:16.000Z"
      }
    ]
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}