{
  "id": 3553168,
  "title": "How mutation disrupts cell development, driving region-specific brain tumors",
  "url": "https://urgent.news/2026/08/26/how-mutation-disrupts-cell-development-driving-region-specific-brain",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-08-26T17:00:09.000Z",
  "source": {
    "name": "Medical Xpress",
    "slug": "medical-xpress",
    "url": "https://medicalxpress.com/news/2026-08-mutation-disrupts-cell-region-specific.html"
  },
  "original_language": "en",
  "account": null,
  "summary": "Scientists at St. Jude Children's Research Hospital have shown that specific brain cells respond differently to H3.3 K27M, a mutation in the histone H3.3 protein that drives many cases of diffuse midline glioma (DMG), depending on the cells' location in the developing brain. These findings help explain why DMG, a pediatric brain cancer commonly associated with this mutation, typically arises in…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}