{
  "id": 3532410,
  "title": "Sharpening an essential tool for biotechnology",
  "url": "https://urgent.news/2026/08/26/sharpening-an-essential-tool-for-biotechnology",
  "topic": "science",
  "section": "Science",
  "published": "2026-08-26T15:00:06.000Z",
  "source": {
    "name": "Phys.org",
    "slug": "phys-org",
    "url": "https://phys.org/news/2026-08-sharpening-essential-tool-biotechnology.html"
  },
  "original_language": "en",
  "account": null,
  "summary": "Scientists at the Department of Energy (DOE)'s Oak Ridge National Laboratory (ORNL) have shown that more than 93% of possible E. coli CRISPR-Cas9 guide RNAs—molecules that direct the gene-editing CRISPR tool to the right spot in DNA—work as intended, a far higher percentage than researchers expected. They also discovered why a small number of guides fail and developed a simple way to repair them.…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}