{
  "id": 3327069,
  "title": "Removing immune 'brake' improves CAR T-cell therapy for pediatric bone cancer",
  "url": "https://urgent.news/2026/08/25/removing-immune-brake-improves-car-t-cell-therapy-for-pediatric-bone",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-08-25T18:20:01.000Z",
  "source": {
    "name": "Medical Xpress",
    "slug": "medical-xpress",
    "url": "https://medicalxpress.com/news/2026-08-immune-car-cell-therapy-pediatric.html"
  },
  "original_language": "en",
  "account": null,
  "summary": "Scientists at St. Jude Children's Research Hospital have discovered that removing the gene for Regnase-1 from engineered immune cells makes them more effective at treating relapsed osteosarcoma. There is a great clinical need for new therapies for childhood osteosarcoma, for which there are very few effective treatments for relapsed disease. The approach improved the cells' ability to control…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}