{
  "id": 2369263,
  "title": "Spatiotemporal regulation of LGN/NuMA and astral microtubules generate mirror symmetric spindle rotations",
  "url": "https://urgent.news/2026/08/21/spatiotemporal-regulation-of-lgn-numa-and-astral-microtubules",
  "topic": "science",
  "section": "Science",
  "published": "2026-08-21T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.08.20.745970v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "The positioning of the mitotic spindle controls the size, content, and position of daughter cells within embryos and tissues. A major spindle positioning mechanism is cortical pulling whereby the membrane-bound complex LGN/NuMA/Dynein captures astral microtubules and pulls centrosomes toward the cell cortex. Cytoplasmic dynein and astral growth tend to counteract cortical pulling and position…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}