{
  "id": 2311592,
  "title": "TGF-β2-induced Snail-mediated EndMT signaling relies on both Smad-dependent and independent pathways",
  "url": "https://urgent.news/2026/08/20/tgf-2-induced-snail-mediated-endmt-signaling-relies-on-both-smad",
  "topic": "science",
  "section": "Science",
  "published": "2026-08-20T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.08.17.745236v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Endothelial-to-mesenchymal transition (EndMT) has become a central mechanism in developmental biology, fibrosis, vascular disease, and cancer. We previously reported on an integrated signaling model in which TGF-{beta}2 induces EndMT through coordinated activation of Smad-dependent and Smad-independent signaling pathways converging on Snail, while GSK-3{beta} regulates Snail activity. We…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}