{
  "id": 225603,
  "title": "Fridge-free tetanus-diphtheria vaccine shows promise of reaching millions worldwide",
  "url": "https://urgent.news/2026/08/06/fridge-free-tetanus-diphtheria-vaccine-shows-promise-of-reaching",
  "topic": "science",
  "section": "Science",
  "published": "2026-08-06T15:40:02.000Z",
  "source": {
    "name": "Medical Xpress",
    "slug": "medical-xpress",
    "url": "https://medicalxpress.com/news/2026-08-fridge-free-tetanus-diphtheria-vaccine.html"
  },
  "original_language": "en",
  "account": "A fridge-free tetanus-diphtheria vaccine has shown promising results in early trials, potentially paving the way for wider global distribution and reduced environmental impact. The University of Southampton and University Hospital Southampton NHS Foundation Trust conducted the Phase I trial, which found the vaccine to be safe and effective without the need for refrigeration. This is a significant challenge for many immunization programs worldwide, as keeping vaccines cold from production to administration remains difficult. The reformulated vaccine, called SPVX02, was developed by U.K.-based biotech company Stablepharma using its StablevaX technology. The vaccine remained stable and effective at temperatures up to 30°C (86°F) for at least two years and after repeated temperature fluctuations from -20°C to +40°C. Phase 2b trials are planned to further assess the vaccine's efficacy in a larger group of participants. This breakthrough could transform vaccine delivery, especially in isolated communities and regions affected by conflict, where refrigeration access is limited. Health and Social Care Minister Diana Johnson highlighted the potential of fridge-free vaccines to be a game-changer for global health, particularly in remote areas.",
  "summary": "The encouraging results of the world's first trial of a fridge-free tetanus-diphtheria vaccine could improve access worldwide to crucial treatments while reducing carbon emissions. Fridge-free vaccines have the potential to transform vaccine delivery by reducing dependence on refrigeration. This would improve access in more isolated communities and cut the environmental impact by reducing energy…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}