{
  "id": 2182327,
  "title": "Tumor-tropic E. coli engineered as living T and NK cell engagers",
  "url": "https://urgent.news/2026/08/20/tumor-tropic-e-coli-engineered-as-living-t-and-nk-cell-engagers",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-08-20T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.08.18.745642v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Despite advances in immunotherapy, most solid tumors remain resistant to treatment. Immune cell engagers redirect cytotoxic lymphocytes against cancer, but limited tumor access, immunosuppressive microenvironments and systemic immune activation limit efficacy. Here we develop live immune modulating engagers (LIME), a modular platform where non-pathogenic, tumor-tropic Escherichia coli display…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}