{
  "id": 20125224,
  "title": "Discovery of molecular glues for modulating MHC presentation of cancer neoantigens",
  "url": "https://urgent.news/2026/11/14/discovery-of-molecular-glues-for-modulating-mhc-presentation-of",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-11-14T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.11.13.762685v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Antigen presentation by MHC class I molecules is essential for cancer immunosurveillance, but many cancer-specific antigens fail to form complexes with Class I MHC and are poorly presented on the cell surface. In this study, we present a chemical strategy to overcome this limitation by identifying peptide MHC glues (PMGs) that promote the formation of peptide-MHC complexes with otherwise…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}