{
  "id": 2004788,
  "title": "Hippocampal information topology breaks down in a mouse model of Alzheimer's disease",
  "url": "https://urgent.news/2026/08/19/hippocampal-information-topology-breaks-down-in-a-mouse-model-of",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-08-19T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.08.14.744888v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Hippocampal spatial coding depends on coordination among neuronal assemblies, yet how network topology organises information processing across these assemblies, and how this is disrupted in disease, remain unknown. We apply Partial Information Decomposition to CA1 calcium imaging from young and aged wild-type and 5xFAD mice, quantifying redundant and synergistic information sharing within and…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 2,
    "also_reported_by": [
      {
        "outlet": "bioRxiv",
        "title": "Myelin maturation failure and oligodendrocyte precursor loss underlie default mode network disruption in a humanized APP knock-in model of Alzheimer's disease",
        "url": "https://urgent.news/2026/08/17/myelin-maturation-failure-and-oligodendrocyte-precursor-loss-underlie",
        "published": "2026-08-17T00:00:00.000Z"
      }
    ]
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}