{
  "id": 19854143,
  "title": "Amyloidosis and tauopathy progressively disrupt near-critical dynamics in selectively vulnerable circuits",
  "url": "https://urgent.news/2026/11/13/amyloidosis-and-tauopathy-progressively-disrupt-near-critical",
  "topic": "science",
  "section": "Science",
  "published": "2026-11-13T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.11.11.766020v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Mechanistically distinct neurodegenerative diseases result in similar cognitive deficits, and pathology is often concentrated in a set of circuits known to be selectively vulnerable. Selective vulnerability is an intrinsic property of a circuit: in APP/PS1 mice, where plaques are global, functional disruptions are confined to circuits within the default mode network. What characterizes the…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}