{
  "id": 19854139,
  "title": "Multivalent BBSome-IFT proximities support IFT-A-IFT-B coordination in vivo",
  "url": "https://urgent.news/2026/11/13/multivalent-bbsome-ift-proximities-support-ift-a-ift-b-coordination",
  "topic": "science",
  "section": "Science",
  "published": "2026-11-13T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.11.11.765876v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Intraflagellar transport (IFT) depends on coordinated movement of IFT-A and IFT-B, yet how these assemblies remain coupled within dynamic ciliary trains is unclear. Here, we combine endogenous fluorescent knock-in tagging, quantitative in vivo FLIM-FRET, structural modeling, and targeted mutagenesis to define IFT organization in C. elegans and mammalian cells. FLIM-FRET mapping identifies…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}