{
  "id": 19854132,
  "title": "ECMExplainer: a functional matrisome framework for decoding cellular stress states and aging trajectories",
  "url": "https://urgent.news/2026/11/13/ecmexplainer-a-functional-matrisome-framework-for-decoding-cellular",
  "topic": "science",
  "section": "Science",
  "published": "2026-11-13T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.11.11.766024v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "The extracellular matrix (ECM) is increasingly recognized as both a hallmark of aging and a durable record of the cellular stress states that shape age-related tissue dysfunction. Despite its apparent role in aging and disease, translating matrisome gene expression into interpretable biological meaning remains an unresolved challenge. Here we introduce ECMExplainer, a framework that uses 180…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}