{
  "id": 19838449,
  "title": "Peptide-centric proteomics reveals molecular subtypes of sporadic Alzheimer's disease",
  "url": "https://urgent.news/2026/11/13/peptide-centric-proteomics-reveals-molecular-subtypes-of-sporadic",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-11-13T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.11.12.766321v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Alzheimer's disease (AD) is a complex, age-related disease that continues to increase in incidence worldwide. Although some cases are caused by known pathogenic mutations, the majority of cases are sporadic, with uncertain etiology and commonly complicated by comorbid diseases. To better understand the molecular landscape of AD we constructed a unique brain sample set free from neuropathologic…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 6,
    "also_reported_by": [
      {
        "outlet": "Medical Xpress",
        "title": "Alzheimer's discovery reveals brain cleaning gone wrong",
        "url": "https://urgent.news/2026/11/10/alzheimers-discovery-reveals-brain-cleaning-gone-wrong",
        "published": "2026-11-10T17:00:01.000Z"
      },
      {
        "outlet": "Nature",
        "title": "New culprit in early Alzheimer’s: Blood–brain barrier blocks protective proteins",
        "url": "https://urgent.news/2026/11/11/new-culprit-in-early-alzheimers-blood-brain-barrier-blocks-protective",
        "published": "2026-11-11T00:00:00.000Z"
      },
      {
        "outlet": "PsyPost",
        "title": "Brain wiring patterns of SuperAgers may help flag Alzheimer’s risk years before symptoms",
        "url": "https://urgent.news/2026/11/11/brain-wiring-patterns-of-superagers-may-help-flag-alzheimers-risk",
        "published": "2026-11-11T17:00:25.000Z"
      },
      {
        "outlet": "El Pais English",
        "title": "Scientists create largest-ever map of brain region tied to Parkinson’s, Alzheimer’s, schizophrenia and autism",
        "url": "https://urgent.news/2026/11/12/scientists-create-largest-ever-map-of-brain-region-tied-to-parkinsons",
        "published": "2026-11-12T17:50:31.000Z"
      },
      {
        "outlet": "ETHealthworld",
        "title": "Blood-brain barrier discovery could lead to new Alzheimer's disease approach",
        "url": "https://urgent.news/2026/11/14/blood-brain-barrier-discovery-could-lead-to-new-alzheimers-disease",
        "published": "2026-11-14T02:14:35.000Z"
      }
    ]
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}