{
  "id": 1982104,
  "title": "Brain-wide reconfiguration of burst firing by psilocybin reveals 5-HT2A-dependent circuit dynamics",
  "url": "https://urgent.news/2026/08/19/brain-wide-reconfiguration-of-burst-firing-by-psilocybin-reveals-5",
  "topic": "science",
  "section": "Science",
  "published": "2026-08-19T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.08.14.744865v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Psilocybin produces rapid and lasting therapeutic effects, yet how 5-HT2A receptor activation reshapes brain-wide circuit dynamics during acute drug administration remains poorly understood. Using simultaneous multi-region Neuropixels recordings of 46,360 single units from 35 mice, together with scalp electroencephalography (EEG), pupillometry, and locomotion monitoring, we provide a brain-wide,…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}