{
  "id": 19605053,
  "title": "Comparative functional genomics reveals distributed SERPINE1 like characteristics among Drosophila serpins",
  "url": "https://urgent.news/2026/11/11/comparative-functional-genomics-reveals-distributed-serpine1-like",
  "topic": "science",
  "section": "Science",
  "published": "2026-11-11T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.11.02.763793v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Serpins (serine protease inhibitors) regulate proteolytic activity through a suicide-substrate inhibitory mechanism, whereby the serpin covalently traps and inactivates their target protease. Serpins are broadly conserved across eukaryotes, but the evolutionary and functional relationships between human SERPINE1, and Drosophila Serpins in incompletely defined. To identify candidate Drosophila…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}