{
  "id": 19576671,
  "title": "A multi- tissue atlas of age-associated differential transcript usage in mouse reveals predominantly regulatory isoform switching across brain, liver, and adipose",
  "url": "https://urgent.news/2026/11/11/a-multi-tissue-atlas-of-age-associated-differential-transcript-usage",
  "topic": "science",
  "section": "Science",
  "published": "2026-11-11T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.11.10.765779v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Alternative splicing is increasingly recognized as dysregulated in the aging process across tissues and affects proteome and other regulatory changes which can be biomarkers of aging. In this study, we aimed to identify differential transcript usage (DTU) and isoforms switch accompanied with functional annotation and structural analysis in mouse brain, liver and adipose tissue during natural…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}