{
  "id": 1951182,
  "title": "Optimizing 3D Spheroid Formation in Microwells via a Simple Pluronic F127 Coating",
  "url": "https://urgent.news/2026/08/19/optimizing-3d-spheroid-formation-in-microwells-via-a-simple-pluronic",
  "topic": "science",
  "section": "Science",
  "published": "2026-08-19T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.08.18.744263v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Three-dimensional (3D) spheroid culture provides a physiologically relevant alternative to conventional two-dimensional culture, but reliable spheroid formation in microwells depends on limiting cell-substrate adhesion. Pluronic F127 is an amphiphilic triblock copolymer that forms a hydrated surface layer, reducing protein adsorption. Here, we evaluated whether this intrinsic anti-fouling…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}