{
  "id": 1951173,
  "title": "Time-Resolved Phenotypic and Transcriptomic Responses of Primary Canine Dermal Fibroblasts to Prolonged Hypothermic Stress",
  "url": "https://urgent.news/2026/08/19/time-resolved-phenotypic-and-transcriptomic-responses-of-primary",
  "topic": "science",
  "section": "Science",
  "published": "2026-08-19T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.08.14.744362v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Prolonged low-temperature exposure may extend the preservation window of mammalian cells but can also disrupt cellular homeostasis and ultimately compromise cell viability. This study investigated the time-dependent phenotypic and transcriptomic responses of primary canine dermal fibroblasts to sustained hypothermic stress. Passage-three fibroblasts were continuously maintained at 15 for up to 15…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}