{
  "id": 19404284,
  "title": "Computational model of developmental self-assembly of a cortical microcircuit",
  "url": "https://urgent.news/2026/11/10/computational-model-of-developmental-self-assembly-of-a-cortical",
  "topic": "science",
  "section": "Science",
  "published": "2026-11-10T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.11.09.762492v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Cortical microcircuits emerge from local developmental interactions, yet large-scale computational models typically prescribe connectivity rather than explain its formation. Here we use BioDynaMo to simulate the self-assembly of ~70,000 cortical neurons from 1,200 progenitors in 3D physical space through migration, neurite growth and contact-based synapse formation. With one calibrated filling…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}