{
  "id": 19326355,
  "title": "Alveolar and airway progenitors converge on an epigenetically encoded profibrotic state",
  "url": "https://urgent.news/2026/11/10/alveolar-and-airway-progenitors-converge-on-an-epigenetically-encoded",
  "topic": "science",
  "section": "Science",
  "published": "2026-11-10T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.11.08.765110v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "During organ regeneration, epithelial transitional states arise from progenitors and instruct the mesenchyme to remodel the extracellular matrix. However, the identity of the progenitors, the mechanisms underlying this transition, and why these states persist in tissue fibrosis often remain elusive. Here, using lineage tracing in mice, we show that the profibrotic KRT5-/KRT17+ state in pulmonary…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}