{
  "id": 19178684,
  "title": "MaaD-TAD: an all-atom model of the duplicated PRAMEF/HNRNPCL chromatin domain built from sequence homology",
  "url": "https://urgent.news/2026/11/09/maad-tad-an-all-atom-model-of-the-duplicated-pramef-hnrnpcl-chromatin",
  "topic": "science",
  "section": "Science",
  "published": "2026-11-09T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.29.762793v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "In the nucleus, the placement of genes in the 3D fold of DNA affects how they function. Models of this fold use two kinds of data: contact maps constructed from Hi-C, and nucleosome maps showing where DNA is wound around nucleosomes. Over evolution, sections of the genome were copied, creating near-identical regions. Reads from these regions cannot be assigned to one copy and are discarded,…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}