{
  "id": 1855573,
  "title": "Transposon mutagenesis uncovers the genetic landscape of streptomycin susceptibility and implicates SbmA in aminoglycoside uptake in Escherichia coli",
  "url": "https://urgent.news/2026/08/18/transposon-mutagenesis-uncovers-the-genetic-landscape-of-streptomycin",
  "topic": "science",
  "section": "Science",
  "published": "2026-08-18T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.08.18.745456v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Aminoglycosides are critical antibiotics with partially elucidated mechanisms of uptake and action in Gram-negative bacteria. Importantly, although energy-dependent uptake across the inner membrane has been well-established, the specific molecular mechanisms involved have not been definitively identified. To deepen understanding of genetic factors influencing susceptibility and resistance to…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}