{
  "id": 18185312,
  "title": "CloneVI: A deep generative model for deciphering the relationships between cell state and mitochondrial genotype",
  "url": "https://urgent.news/2026/11/04/clonevi-a-deep-generative-model-for-deciphering-the-relationships",
  "topic": "science",
  "section": "Science",
  "published": "2026-11-04T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.11.03.764043v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Cellular diversity arises from both genetic lineages and non-genetic regulation of cell states, and knowing which cell states are tied to lineages is central to understanding how clones shape disease. Single-cell multi-omics technologies measure mitochondrial DNA mutations together with gene expression or chromatin accessibility in the same cells, but clones are usually inferred from mutations…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}