{
  "id": 18185306,
  "title": "Facilitating the identification of cryo-EM hit matter in drug discovery with Astex-Faro",
  "url": "https://urgent.news/2026/11/04/facilitating-the-identification-of-cryo-em-hit-matter-in-drug",
  "topic": "science",
  "section": "Science",
  "published": "2026-11-04T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.11.03.763890v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Cryogenic electron microscopy (cryo-EM) is emerging as a tool for large-scale ligand screening and fragment-based drug discovery, generating extensive collections of reconstructions. At the same time, the systematic inspection of local density variations remains challenging, particularly when identifying weak or partially occupied features. Here, we present Astex-Faro, a statistical framework…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}