{
  "id": 18085670,
  "title": "Herboxidiene and EGFR expression in A172 glioblastoma cells",
  "url": "https://urgent.news/2026/11/03/herboxidiene-and-egfr-expression-in-a172-glioblastoma-cells",
  "topic": "science",
  "section": "Science",
  "published": "2026-11-03T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.11.02.762382v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Glioblastoma carries a five-year survival of about 10%, and EGFR amplification is one of the molecular criteria that define the disease in the 2021 WHO classification of central nervous system tumours. SF3b inhibitors, which displace the U2 snRNP from the intron branch point, suppress EGFR expression in lung adenocarcinoma cells by causing retention of EGFR intron 2. We asked whether the same…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}