{
  "id": 18027832,
  "title": "AI may help tailor treatment for childhood brain tumors",
  "url": "https://urgent.news/2026/11/03/ai-may-help-tailor-treatment-for-childhood-brain-tumors",
  "topic": "ai",
  "section": "AI",
  "published": "2026-11-03T21:40:06.000Z",
  "source": {
    "name": "Medical Xpress",
    "slug": "medical-xpress",
    "url": "https://medicalxpress.com/news/2026-11-ai-tailor-treatment-childhood-brain.html"
  },
  "original_language": "en",
  "account": null,
  "summary": "An international team of researchers, led by scientists at Dana-Farber Cancer Institute, has developed an artificial intelligence model called MANTIS (Methylation profiling and Artificial Neural networks for Time-dependent Individualized Survival predictions). This AI model uses DNA methylation profiling, a test already used to diagnose brain tumors, to generate personalized survival predictions for children with medulloblastoma and ependymoma. The study, published in Nature Genetics, found that MANTIS outperformed current risk-prediction approaches for many patients and could potentially reduce treatment intensity in some children with medulloblastoma. By estimating how survival probability changes over time based on the unique biology of each child's tumor, MANTIS aims to move beyond broad risk categories and provide a more individualized understanding of each child's tumor. This could help match treatment intensity to the biology of the disease and reduce long-term side effects for some patients.",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}