{
  "id": 17950006,
  "title": "FoXSight: Facilitating Computational Hit Identification in Crystallographic Fragment Screening Experiments",
  "url": "https://urgent.news/2026/11/03/foxsight-facilitating-computational-hit-identification-in",
  "topic": "science",
  "section": "Science",
  "published": "2026-11-03T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.11.01.763443v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "X-ray crystallographic fragment screening reveals how small molecules bind to proteins, providing important starting points for drug design. Identifying these weak binding events remains difficult when electron density signals are noisy, partially occupied or obscured by solvent, and campaigns may comprise thousands of datasets. Here, we present FoXSight, a computational method for hit…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}