{
  "id": 17935360,
  "title": "Fentanyl and fentanyl-xylazine co-exposure influence mitochondrial transcriptional programs in human trophoblasts",
  "url": "https://urgent.news/2026/11/02/fentanyl-and-fentanyl-xylazine-co-exposure-influence-mitochondrial",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-11-02T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.31.763373v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Introduction: Illicit fentanyl exposure during pregnancy is associated with adverse outcomes. Yet its direct effects and their underlying molecular mechanisms in human trophoblasts remain largely unknown. Xylazine and medetomidine, two [a]2-adrenergic agonists, were recently detected as adulterants in illicit fentanyl-containing products, and have been linked to worsened clinical outcomes.…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}