{
  "id": 17928289,
  "title": "Refining RNA-Seq Transcriptome Profiles with Transcript-Specific Minimal-Shared Regions",
  "url": "https://urgent.news/2026/11/02/refining-rna-seq-transcriptome-profiles-with-transcript-specific",
  "topic": "science",
  "section": "Science",
  "published": "2026-11-02T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.28.762701v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Accurate transcript quantification remains a critical challenge in RNA sequencing (RNA-seq) due to ambiguities in read assignment caused by shared regions among transcripts. Beyond shared exons among homologous isoforms, we identified the widespread presence of extensive undefined shared regions-overlapping sequences common to exons or transcripts of heterologous genes-across diverse species,…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}