{
  "id": 17928285,
  "title": "How Well Does Structural MRI Classify Autism? A Leakage-Free, Site-Aware and Externally Validated Machine-Learning Evaluation in Two ABIDE Cohorts",
  "url": "https://urgent.news/2026/11/02/how-well-does-structural-mri-classify-autism-a-leakage-free-site",
  "topic": "science",
  "section": "Science",
  "published": "2026-11-02T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.31.763319v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Background: Many studies report high accuracy for classifying autism spectrum disorder (ASD) from structural MRI, but small samples, single train-test splits, site effects and information leakage can inflate performance. We evaluated how well brain morphometry distinguishes autistic from typically developing (TD) individuals under rigorous, leakage-free validation. Methods: FreeSurfer-derived…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}