{
  "id": 17825112,
  "title": "Coding region changes in the Hippo pathway component YAP1 contribute to body size differences among mammalian species",
  "url": "https://urgent.news/2026/11/02/coding-region-changes-in-the-hippo-pathway-component-yap1-contribute",
  "topic": "science",
  "section": "Science",
  "published": "2026-11-02T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.29.762931v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Animal species differ dramatically in their overall size, yet the mechanisms underlying these differences are poorly understood. The Hippo pathway, first discovered in Drosophila, and widely conserved in mammals, regulates the nuclear levels of YAP1, a transcriptional co-activator that enhances the expression of growth-promoting genes. While experimental manipulations of this pathway elicit…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}