{
  "id": 17825105,
  "title": "Filament assembly confers the mechanical resilience of the IFI16 restrictosome",
  "url": "https://urgent.news/2026/11/02/filament-assembly-confers-the-mechanical-resilience-of-the-ifi16",
  "topic": "science",
  "section": "Science",
  "published": "2026-11-02T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.30.763160v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Interferon-inducible protein 16 (IFI16) is a mammalian innate immune sensor composed of a filament-forming pyrin domain (PYD) followed by tandem HIN200 domains that bind nucleic acids. First recognized as a major regulator of inflammatory responses against cytosolic double-stranded (ds)DNA, IFI16 filaments have been implicated in several key mechanical processes involving both host and pathogens,…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}