{
  "id": 17399087,
  "title": "Neutrophil RAGE drives early cerebrovascular injury after subarachnoid hemorrhage",
  "url": "https://urgent.news/2026/10/31/neutrophil-rage-drives-early-cerebrovascular-injury-after",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-31T12:00:05.000Z",
  "source": {
    "name": "Medical Xpress",
    "slug": "medical-xpress",
    "url": "https://medicalxpress.com/news/2026-10-neutrophil-rage-early-cerebrovascular-injury.html"
  },
  "original_language": "en",
  "account": null,
  "summary": "An international research team led by Assistant Professor Hiroshi Ishii and Professor Osamu Hori has identified neutrophil RAGE (receptor for advanced glycation end products) as a key driver of early cerebrovascular injury after subarachnoid hemorrhage (SAH). The study, published in the Journal of Cerebral Blood Flow & Metabolism, shows that neutrophil RAGE promotes neutrophil accumulation around cerebral arteries, cerebral vasospasm, impaired cortical circulation and neurological dysfunction. The findings suggest that an immediate sympathetic vascular response is followed by a neutrophil RAGE-dependent inflammatory phase, which may help identify earlier, mechanism-based therapeutic strategies for SAH.",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}